One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the ...
Jul 4, 2012
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Fibronectin plays a major role in wound healing and embryonic development. The protein, which is located in the extracellular matrix of cells, has also been linked to pathological conditions including cancer and fibrosis.
Apr 24, 2012
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(Medical Xpress) -- UCLA stem-cell researchers have identified a certain type of cell and a signaling pathway in the placental niche that play a key role in stopping blood stem cells from differentiating into mature blood ...
Mar 1, 2012
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Scientists with the new Children's Research Institute at UT Southwestern Medical Center have identified the environment in which blood-forming stem cells survive and thrive within the body, an important step toward increasing ...
Jan 25, 2012
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The complex interplay between extracellular genetic material and the tumor's genetic landscape presents a significant challenge in grasping cancer evolution, tumor genetic heterogeneity, and treatment response. Earlier research ...
Aug 9, 2024
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Researchers probing the next frontiers in cancer therapy have turned to bacteria given their ability to inhibit tumor proliferation by colonizing tumors. Crucially, the Achilles heel of this approach is suboptimal treatment ...
Jul 1, 2024
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While the overall five-year survival rate for pancreatic cancer is slowly improving, it remains discouragingly low—just 13%, according to the American Cancer Society. And the odds are even worse if the cancer is discovered ...
Jun 24, 2024
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The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor. Over time, the tumor shapes this ...
Jun 13, 2024
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Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development. During the development of tumors ("tumorigenesis"), collagen fibers become linearized and densely deposited, hindering immune ...
May 23, 2024
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Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms. The tumor microenvironment plays a pivotal role in fostering ...
May 22, 2024
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