Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.
Nov 13, 2023
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Scientists at the University of Liverpool have figured out how mutations in a gene called FBXL4 can lead to an excess of mitophagy—the disposal of mitochondria, the 'power stations' within nearly all human cells.
May 4, 2023
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The words that researchers use to describe their results can be harnessed to discover potential new treatments for Parkinson's disease, according to a new study publishing March 2nd in the open access journal PLoS Biology ...
Mar 2, 2023
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While most commonly known as "the powerhouses of the cell" because of their energy producing capabilities, mitochondria also play important roles in regulating the health of cells. These important structures can be damaged ...
May 24, 2022
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The loss of muscle tissue—referred to as muscle atrophy in medical terms—can occur as a result of lack of physical activity for an extended period of time; aging; alcohol-associated myopathy—a pain and weakness in muscles ...
Jun 15, 2021
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In the journal Nature Communications, researchers reveal a novel molecular mechanism underlying the detrimental effects of uncontrolled mitophagy on neuronal survival that contributes to the development and progression of ...
Aug 20, 2020
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A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria ...
Aug 14, 2020
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Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations ...
Oct 16, 2019
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An international research team with representation from the University of Copenhagen has created a better understanding of Alzheimer's. They have shown that the cleaning system of the brain cells, a process called mitophagy, ...
Feb 15, 2019
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