T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, ...
Mar 4, 2024
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In findings that are nothing short of surprising, scientists have demonstrated that the liver is the site where the immune system unleashes its assault on pneumococcal bacteria following vaccination against the potentially ...
The candidate gene FKBP5 is involved in the development of stress-related psychiatric disorders. A few years ago, researchers at the MPI discovered that it is increasingly activated in the brains of patients and can permanently ...
Feb 27, 2024
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Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study focusing on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the ...
Feb 27, 2024
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In experiments with lab-grown brain cells and mouse models, scientists at Johns Hopkins Medicine say they have discovered that a cell surface protein called Lag3 is not only a biological target for FDA-approved drugs that ...
Feb 23, 2024
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With a newly developed mouse model that more accurately represents human infection with COVID-19, Johns Hopkins scientists say they have found long-term infection with SARS-CoV-2 results in brain deposits of clumped and tangled ...
Feb 23, 2024
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What causes us to age? New "clocks" developed by researchers may help point to the answers. Investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, unveil a new form ...
Feb 14, 2024
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Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting pathogenesis features neuroinflammation, ...
Feb 12, 2024
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Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers ...
Feb 8, 2024
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During pregnancy, the human placenta plays multiple essential roles, including hormone production and nutrient/waste processing. It also serves as a barrier to protect the developing fetus from external toxic substances. ...
Feb 8, 2024
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