All viruses mutate as they make copies of themselves to spread and thrive. SARS-CoV-2, the virus the causes COVID-19, is proving to be no different. There are currently more than 4,000 variants of COVID-19, which has already ...
Mar 23, 2021
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A notable characteristic of several neurodegenerative diseases, such as Alzheimer's and Parkinson's, is the formation of harmful plaques that contain aggregates—also known as fibrils—of amyloid proteins. Unfortunately, ...
Aug 4, 2020
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Alzheimer's disease (AD), a severe form of dementia among aged individuals, is caused by accumulation of amyloid-beta (Aβ) peptides in the brain. Numerous types of agents have been developed to suppress the production of ...
Jun 11, 2015
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Researchers from the National Institutes of Natural Sciences and Nagoya City University have achieved a significant breakthrough by elucidating the structure of amyloid β (Aβ) bound to glycolipids on the surface of nerve ...
Aug 7, 2023
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Siglec-15 has emerged as a promising target for therapeutic intervention in the field of cancer treatment, primarily due to its unique expression pattern and potential as an immune modulator. Its distinct expression profile, ...
Jun 16, 2023
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A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in ...
Apr 4, 2024
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The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection. Now, researchers ...
Apr 28, 2021
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Molecular simulations on the JUWELS supercomputer show how the HIV-1 virus is able to evade the human immune system. The newly discovered mechanism could prove to be the Achilles' heel of the virus and open new doors for ...
Feb 28, 2024
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Researchers at the University of Delaware, working with colleagues at Indiana University, have gained new insights into the virus that causes hepatitis B—a life-threatening and incurable infection that afflicts more than ...
Jun 1, 2018
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A global race is underway to discover a vaccine, drug, or combination of treatments that can disrupt the SARS-CoV-2 virus, which causes the COVID-19 disease, and prevent widespread deaths.
Apr 22, 2020
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