Diseases, Conditions, Syndromes

Respiratory tract bacterial extracts could prevent COVID-19

Researchers from the UArizona College of Medicine—Tucson found that the bacterial lysate OM-85 blocked SARS-CoV-2 infection by decreasing the ability of the coronavirus to bind to the lung cell surface receptor ACE2.

Medications

The impact of drugs on gut microbes is greater than we thought

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute ...

Gastroenterology

Scientists pinpoint key trigger of Crohn's disease

A new treatment may be on the horizon for people with a major form of inflammatory bowel disease (IBD) called Crohn's disease, after a McMaster University-led study identified serotonin as a possible trigger of flare-ups. ...

Medications

Patent granted for drug candidate intended for cancer treatment

A potential new drug candidate developed by researchers at the University of Oulu, Finland, has been granted a patent in the United States. The drug is a small molecular chemical compound that is especially suited for cancer ...

Oncology & Cancer

Understanding the tricks of lymphomas

Cellular immunotherapies have so far not been very effective against non-Hodgkin's lymphoma. A team led by Armin Rehm of the MDC has discovered a possible reason. As the they describe in Cell Reports, this cancer induces ...

Oncology & Cancer

Exploiting cancer's sweet tooth to develop a treatment

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring ...

Oncology & Cancer

The signatures of peritoneal metastases

Surgical removal of the primary tumor is usually not enough. One in two colorectal cancer patients develops distant metastases. In about 30 percent of the cases, they appear in the lining of the abdominal cavity—the peritoneum. ...

Immunology

Scientists identify Tox2 as a key regulator of TFH immune cells

Vaccines have been a mainstay in modern medicine since the late 18th Century, but there is evidence that societies have been using them for more than a thousand years. Throughout this time, all vaccines have operated by activating ...

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