Genetics

One gene predicts rapid ALS progression 80 percent of the time

(Medical Xpress)—The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in an upcoming ...

Genetics

The naked mole-rat's secret to staying cancer free

A team of researchers from the University of Rochester (NY) and the University of Haifa discovered the naked mole rat's unique mechanism to staying cancer free- a super sugar called high-molecular-mass Hyaluronan (HMM-HA). ...

Oncology & Cancer

Boosting the immune response against cancer

T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...

Immunology

Transporter's role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction ...

Oncology & Cancer

Researchers identify mechanism that makes breast cancer invasive

A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press on March 30th in the journal Molecular Cell, enhances our knowledge about the signals that drive cancer ...

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