Many neurodevelopmental disorders such as epilepsy, schizophrenia, and autism have been linked to disruption of the key neurotransmitter GABA, but the underlying causes of the disruptions have been difficult to pinpoint. ...
Oct 17, 2019
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There's a good, bad and ugly to cancer chemotherapy. The good is that the drugs do often effectively kill cancer cells. The bad is that the drugs also damage other quickly dividing cells in the body, causing side effects ...
Jun 16, 2016
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Northwestern Medicine investigators have discovered novel sex-specific mechanisms that control how stress hormones impact dopamine transmission and motivation, findings that can inform new therapeutic strategies for treating ...
Mar 24, 2023
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Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...
May 5, 2022
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In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.
Sep 4, 2011
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Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant ...
Jan 24, 2023
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Scientists have found the 'key' that HIV uses to enter our cells' nuclei, allowing it to disable the immune system and cause AIDS The finding, published today in the open access journal PLoS Pathogens, provides a potential ...
Dec 8, 2011
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New research has shown that the antidepressant sertraline inhibits the growth of cancer cells. It acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and ...
Nov 17, 2020
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Researchers have taken a critical step in understanding how allergic reactions occur after identifying a genetic signature for regulation of a key immune hormone, interleukin (IL-13).
Mar 28, 2012
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An international team of scientists led by researchers at the University of California, San Diego School of Medicine have used induced pluripotent stem cells (iPSCs) derived from patients with amyotrophic lateral sclerosis ...
Jun 21, 2011
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