Medical research

Stay-at-home transcription factor prevents neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...

Genetics

How mutations in a high risk gene affect motor neurons

Scientists at the flagship motor neuron disease research centre, based at the University of Sheffield, investigated how specialised nerve cells that control voluntary movements die – something which is key to understanding ...

Neuroscience

Immunity key to motor neurone disease treatment

Customized immune-blocking medication may be the key to treating patients with motor neurone disease (MND), which currently has no cure and limited therapeutic options.

Medical research

UK study finds diaphragm pacing not beneficial to MND patients

A pioneering trial investigating the safety and efficacy of diaphragm pacing used to alleviate breathing difficulties for people with motor neurone disease (MND), has revealed the intervention is not generally beneficial ...

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