Researchers have identified common and rare gene mutations that increase risk for schizophrenia. Yet it's unclear what biological mechanisms go awry in the brain to cause psychosis and other disabling symptoms, due in part ...
Sep 1, 2023
0
42
Northwestern Medicine scientists have developed a new cellular model of uterine fibroids that stem from common genetic mutations, which will accelerate further research and development of future treatments, according to findings ...
Aug 14, 2023
0
53
New research from The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has successfully reversed hearing loss in mice.
Aug 9, 2023
0
68
Stanford Medicine researchers have found that a common blood condition associated with several diseases may have a protective effect against Alzheimer's disease.
Jun 28, 2023
0
78
Chromatin states and their associated epigenetic information play a crucial role in maintaining the identity of cells as they divide. Histone post-translational modifications (PTMs) are important determinants of the cellular ...
Jun 16, 2023
0
49
Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some people diagnosed with one disorder have symptoms ...
May 12, 2023
0
148
Brain development consists of a sequence of coordinated steps, which are mainly instructed by our genes. During these steps, the proper positioning and functionality of nerve cells in the brain (neurons) are critical—nonfunctional ...
Mar 29, 2023
0
222
Bipolar disorder (BD) is a debilitating condition characterized by alternating states of depression (known as depressive episodes) and abnormal excitement or irritability (known as manic episodes). Large-scale genome-wide ...
Mar 7, 2023
0
128
An international research team led by Dr. Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing ...
Dec 12, 2022
0
4
The cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR) gene that are associated with the disease. The tail end of this gene's mutated ...
Sep 20, 2022
0
5
