Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia (CHOP) have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, ...
Mar 13, 2019
0
0
The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumour cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.
Jan 31, 2019
0
13
Neuroblastoma, a disease of immature nerve cells, is the most common solid tumor cancer occurring in children. About 700 new cases are diagnosed in the U.S. each year with approximately half of these children developing high-risk ...
Oct 4, 2018
0
0
Dr. Kenneth Alexander was driving home one day last year when he thought of the idea: What if the Zika virus could be used to kill a childhood cancer called neuroblastoma?
Jul 25, 2018
0
1
Researchers at VCU Massey Cancer Center in Richmond, Virginia, have identified a promising target to reverse the development of high-risk neuroblastoma and potentially inform the creation of novel combination therapies for ...
Jun 18, 2018
0
31
Researchers at Karolinska Institutet and Karolinska University Hospital have discovered that an anti-inflammatory drug candidate inhibiting the prostaglandin E2 producing enzyme mPGES-1 in the tumour stroma reduces tumour ...
May 29, 2018
0
4
Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages—a type of immune cell—can negatively ...
Apr 24, 2018
0
6
A discovery sheds light on how cancerous cells differ from healthy ones, and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers in the future.
Mar 8, 2018
0
11
Neuroblastoma, a cancer that starts in nerve tissue outside of the brain, is the third most common cancer in children and accounts for about 15 percent of pediatric cancer-related deaths.
Feb 15, 2018
0
1
The female sex hormone oestrogen can perform an important role in neuroblastoma, a form of cancer mainly affecting young children. In laboratory experiments, researchers at Karolinska Institutet in Sweden demonstrate that ...
Jan 29, 2018
0
11
