Oncology & Cancer
Cancer hijack
Genetically unstable breast cancer cells appear to hijack a mechanism used by healthy stem cells to determine how they should develop into different tissues, according to new research.
Jul 19, 2013
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News tagged with notch pathway
Oncology & Cancer
Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance
A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...
Apr 1, 2013
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Surgery
Differences in bone healing in mice may hold answers to bone healing for seniors
(Medical Xpress)—By studying the underlying differences in gene expression during healing after a bone break in young versus aged mice, Jaimo Ahn, MD, PhD, assistant professor of Orthopaedic Surgery at the Perelman School ...
Mar 21, 2013
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Medical research
A better bone marrow transplant: Preventing graft-versus-host disease
Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Mar 1, 2013
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Medical research
Ruling the airways: Notch controls bronchial cell fates and distributions
Nestled deep within the body, the epithelial lining of the respiratory system is nonetheless seriously exposed. Its direct contact with environmental air necessitates protective mechanisms that both seal off the respiratory ...
Jan 22, 2013
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Oncology & Cancer
Notch control of cell architecture: Potential implications for future cancer therapy
Dissecting the mechanisms implicated in cell architecture should provide new insights for understanding development and tissue morphogenesis in general. An European study focused on the role of the Notch signalling pathway ...
Oct 5, 2012
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Medical research
At the right place at the right time—new insights into muscle stem cells
Muscles have a pool of stem cells which provides a source for muscle growth and for regeneration of injured muscles. The stem cells must reside in special niches of the muscle for efficient growth and repair.
Sep 17, 2012
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Medical research
Astrocytes control the generation of new neurons from neural stem cells
Astrocytes are cells that have many functions in the central nervous system, such as the control of neuronal synapses, blood flow, or the brain's response to neurotrauma or stroke.
Aug 24, 2012
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Immunology
Scientists find new mechanism by which cell signaling pathway contributes to rheumatoid arthritis development
A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence ...
May 20, 2012
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Medical research
Gatekeeper signal controls skin inflammation
A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" ...
Jan 26, 2012
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