Medical research

Smaller eggs enhance IVF outcomes for male infertility in mice

A new approach for assisting reproduction in mice when sperm production is faulty has been demonstrated by researchers at RIKEN. It could eventually help human couples who are struggling to conceive by traditional in vitro ...

Genetics

How stress in the intestine influences chromosome inheritance

Inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential for the preservation of all species. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes ...

Medical research

Building the ovarian environment from stem cells

Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were able to apply their findings ...

Obstetrics & gynaecology

Clinics retrieving 'far too many' eggs from IVF patients

Studies indicate that the optimal and safe number of oocytes needed for achieving an ongoing pregnancy is between six and 15. However, the use of egg freezing, frozen embryo replacement (FER) cycles and aggressive stimulation ...

Medical research

Ageing impairs critical final egg maturation stage

Age may adversely affect women's fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according ...

Genetics

Human egg cells are imperfect surprisingly often

More than 7% of human oocytes contain at least one exchangeless chromosome pair, demonstrating a remarkably high level of meiotic recombination failure, finds a study appearing December 10 in the American Journal of Human ...

Medical research

A study reveals potential causes of female infertility

Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and Ph.D. student Ilmatar Rooda from the TalTech Department of Chemistry and Biotechnology have studied genes previously ...

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Oocyte

An oocyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC) which undergoes a mitotic division to form an oogonium. During oogenesis the oogonium becomes a primary oocyte (pronounced oh'a-site).

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