Diseases, Conditions, Syndromes
Modulating bone cell recruitment to prevent osteoporosis
NUS biologists have identified a pathway to reduce bone resorption and maintain bone health for potentially better treatment outcomes.
Jul 28, 2020
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125
News tagged with osteoclast
Medical research
Messages sent by osteoblasts to osteoclasts are enclosed in an extracellular vesicle
In a study published recently in Communications Biology, researchers led by Kanazawa University explain how a tiny fish could help end painful metabolic and genetic bone diseases.
Jul 14, 2020
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1
Medical research
Understanding how bone-dissolving cells are generated
Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms through which macrophages ...
Jun 10, 2020
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3
Medical research
Arginine depletion as a starting point for potential rheumatoid arthritis treatments
Rheumatoid arthritis is a common inflammatory joint disease. A feature of this disease is the increased fusion of endogenous immune cells (macrophages) to form so-called osteoclasts, which attack and break down bone tissue.
Jan 23, 2020
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67
Medical research
'Swiss cheese' bones could be cause of unexplained low back pain
In experiments with genetically engineered and old mice, Johns Hopkins Medicine researchers say they have added to evidence that the vast majority of low back pain in people may be rooted in an overgrowth of pain-sensing ...
Jan 14, 2020
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170
Arthritis & Rheumatism
Researchers split the 'AtoM' in search of a treatment for rheumatoid arthritis
Arthritis is a common chronic disease in which joints become inflamed, leading to stiffness and pain that can often be debilitating. Rheumatoid arthritis (RA) is an autoimmune form of the disease, arising when immune cells ...
Nov 18, 2019
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113
Medical research
Melatonin is a potential drug for the prevention of bone loss during space flight
Melatonin could be a novel drug for preventing bone loss to astronauts during space flight. Here we used goldfish scales as a bone model of coexisting osteoclasts and osteoblasts and demonstrated that melatonin synthesis ...
Sep 3, 2019
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3
Medical research
Study identifies protein responsible for mechanism behind bone loss
Researchers from the UCLA School of Dentistry have provided insight into how the mechanical process of bone loss works and have also identified a protein that is responsible for recycling of the cells that can also promote ...
Aug 8, 2019
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9
Medical research
A link between mitochondrial damage and osteoporosis
Some risk factors for osteoporosis such as being older and female or having a family history of the condition cannot be avoided. But others can, like smoking cigarettes, consuming alcohol, taking certain medications, or being ...
May 9, 2019
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489
Diseases, Conditions, Syndromes
The delicate balance of treating growing but brittle bones
Osteoporosis is a medical condition that causes bones to become fragile and brittle. It is a major health problem worldwide, mainly affecting adults. However, children can also rarely be affected as a result of other diseases ...
Feb 1, 2019
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