When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...
Feb 28, 2024
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Heart failure stands as a leading cause of mortality worldwide, demanding advanced treatment options. Despite the urgency for more effective treatments, options for severe heart failure remain limited. Cell transplantation ...
Feb 21, 2024
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A new research paper was published in Oncotarget is titled, "Osteopontin induces mitochondrial biogenesis in deadherent cancer cells."
Dec 4, 2023
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A new editorial paper was published in Oncotarget, titled "Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors."
Nov 8, 2023
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A new research paper was published in Oncotarget's, titled "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation."
Apr 26, 2023
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A potent and selective colony stimulating factor 1 receptor kinase inhibitor IHMT-CSF1R-833 was discovered by researchers led by Prof. Liu Qingsong from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy ...
Nov 7, 2022
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Diabetic cardiomyopathy (DCM) is a progressive complication associated with type 2 diabetes (T2D), causing deterioration of cardiac function in diabetic patients, independent of coronary artery disease, and hypertension. ...
Sep 28, 2022
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Suffering from the number one cause of death, patients with heart disease are in desperate need of new therapies. However, these new therapies rely on research using heart cells, which are not easy to access. In response, ...
Jun 22, 2021
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Researchers at the University of Eastern Finland have found a potential neuroprotective effect of a protein modification that could be a therapeutic target in early Alzheimer's disease. The new study investigated the role ...
May 19, 2021
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A loss of enzymatic processes within the body can increase a person's risk of bone fracture. This new insight was recently published in eLife by an international team of scientists and engineers led by Deepak Vashishth, the ...
Jan 5, 2021
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