InSysBio continues to investigate the mechanisms underlying Alzheimer's disease (AD) using the quantitative systems pharmacology (QSP) modeling approach. The QSP model describing the tau protein was published in PLOS ONE.
Feb 28, 2018
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A new study has identified novel mechanisms whereby T cells may be able to distinguish an emerging class of targets specifically increased on cancer cells.
Apr 13, 2017
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One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment—before symptoms of memory problems begin to surface. Whether it is ...
Jan 31, 2017
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Scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have discovered that modifications to a protein called RUNX3 may promote cancer progression. The results ...
Jul 15, 2016
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Cancer cells commonly rely on glycolysis, the type of metabolism that does not use oxygen to generate their energy however, researchers from Queen Mary University of London's Barts Cancer Institute and the Spanish National ...
Sep 10, 2015
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In a new study by Sanford Burnham Prebys Medical Discovery Institute (SBP), researchers have identified a novel kinase cascade that regulates mTORC1, a protein complex implicated in the control of cancer cell growth in response ...
Aug 14, 2015
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(HealthDay)—Metformin's role in atherosclerosis may be inhibition of monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation, according to research published online Dec. 31 in Diabetes.
Jan 9, 2015
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UC Irvine scientists studying the role of circadian rhythms in skin stem cells found that this clock plays a key role in coordinating daily metabolic cycles and cell division.
Jan 6, 2015
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Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer's disease without ever showing clinical symptoms in their lifetime.
May 2, 2014
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A new chemical messenger that is critical in protecting the brain against Parkinson's disease has been identified by scientists at the Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit at the ...
Mar 27, 2014
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