Considerable evidence has indicated that the drug metformin, used for more than 50 years to treat type 2 diabetes, also can prevent or slow the growth of certain cancers; but the mechanism behind its anticancer effects has ...
Dec 15, 2016
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A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is ...
Mar 4, 2016
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Johns Hopkins researchers say they have discovered some of the first steps in how a very common gene mutation causes the brain damage associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Aug 26, 2015
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Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped brain cell, called an astrocyte, may play a critical role in health and ...
Aug 17, 2015
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(Medical Xpress)—Epilepsy, irregular heartbeats and other conditions caused by malfunctions in the body's nerve cells, also known as neurons, can be difficult to treat. The problem is that one medicine may help some patients ...
Jul 1, 2013
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(Medical Xpress)—Exactly how Alzheimer's disease kills brain cells is still somewhat of a mystery, but University of Michigan researchers have uncovered a clue that supports the idea that small proteins prick holes into ...
Oct 17, 2012
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Due to the substantial clinical demand for artificial small-diameter vessels (SDVs), numerous commercial products have emerged. However, most existing artificial SDVs lack an endothelial layer, leading to thrombosis. Fabricating ...
Jan 17, 2024
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More than 2.3 million Canadians are affected by osteoporosis, resulting in billions of dollars in economic burden and incalculable suffering.
Nov 2, 2022
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Although the innate immune system is the front line of defense against microbial infections, the complex mechanisms of innate immunity are incompletely understood. In a new study, researchers from Kanazawa University synthesized ...
Jun 23, 2020
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A scar on the elbow that is strained with every movement, or a foot, on which a wound simply does not want to close—poorly healing injuries are a common cause of health restrictions. And although millions of people are ...
Aug 15, 2019
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