A team at the Institute of Neurosciences, joint centre of the Miguel Hernández University (UMH) in Elche and the Spanish National Research Council (CSIC), has published a paper titled "Heteromers of amyloid precursor protein ...
Feb 4, 2015
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It is estimated that about 35 million people worldwide currently suffer from dementia and it is expected that the number will increase to 135 million by the year 2050. The disease is already one of the most common health ...
Dec 8, 2014
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Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of accumulating Aβ in neurons is the ...
Dec 5, 2014
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An innovative laboratory culture system has succeeded, for the first time, in reproducing the full course of events underlying the development of Alzheimer's disease. Using the system they developed, investigators from the ...
Oct 12, 2014
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Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and ...
Jun 30, 2014
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Potential therapies for Alzheimer's disease are currently studied using genetically engineered mouse strains that display many of the key features of the disease. Most of these mouse models overexpress the amyloid precursor ...
Jun 6, 2014
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Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's disease. The researchers ...
Jun 3, 2014
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A research team led by the National Neuroscience Institute (NNI) has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer's disease. This discovery may help researchers ...
Apr 21, 2014
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A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called ...
Apr 20, 2014
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In a study published today in Nature Neuroscience, a group of researchers led by Takaomi Saido of the RIKEN Brain Science Institute in Japan have reported the creation of two new mouse models of Alzheimer's disease that may ...
Apr 13, 2014
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