Medical research

Prion protein protects against epilepsy

In the most systematic and rigorous study conducted thus far in its field, the prion protein (PrPC) was clearly shown to play a role in preventing the onset of epileptic seizures. PrPC is perhaps best known in its 'degenerate' ...

Medical research

Researchers show environment can neutralize lethal proteins

Botching a few folds might transform an origami cow into a deer or sheep. When cellular proteins do the same, they can trigger fatal neurodegenerative diseases that turn the brains of these mammals into dysfunctional sponges.

Medical research

Team finds connection in pathogenesis of neurological diseases, HIV

A new study by George Washington University (GW) researcher Michael Bukrinsky, M.D., Ph.D., shows similarities in the pathogenesis of prion disease—misfolded proteins that can lead to neurological diseases—and the HIV ...

Diseases, Conditions, Syndromes

Naturally occurring antibodies against prion proteins found in humans

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies. The significance is that prion proteins ...

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