Neuroscience

Study suggests potential therapy for Huntington's disease

A new study published in the Proceedings of the National Academy of Sciences (PNAS) suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling ...

Neuroscience

Two proteins offer a 'clearer' way to treat Huntington's disease

In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing ...

Diabetes

Two regimens fail to stop declines in β-cell function

(HealthDay)—Neither glargine followed by metformin nor metformin alone halts the progressive deterioration of β-cell function in youth with impaired glucose tolerance (IGT) or recently-diagnosed type 2 diabetes, according ...

Genetics

Scientists identify ALS disease mechanism

Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons. The ...

Oncology & Cancer

New brain cancer treatment may be more effective, less toxic

(Medical Xpress)—A Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, may change the standard of care for this disease, according to doctors at UC San ...

Alzheimer's disease & dementia

Research identifies new therapeutic target for Alzheimer's disease

Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent ...

Diseases, Conditions, Syndromes

Asian origins of Machado-Joseph disease revealed

(Medical Xpress) -- Knowledge of a disease prevalent among Northern Territory Indigenous communities has been overhauled thanks to research contributed by the University of Sydney's Garth Nicholson.

Parkinson's & Movement disorders

New discovery in fight against Huntington's disease

Researchers at National University of Ireland Galway have made a significant scientific discovery in the fight against Huntington's disease. The novel findings are published 21 February in the online, open access journal ...

Genetics

Gene therapy to reverse heart failure ready for clinical trials

A promising gene therapy developed, in part, at Thomas Jefferson University's Center for Translational Medicine to prevent and reverse congestive heart failure is on the verge of clinical trials, after years of proving itself ...

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