Oncology & Cancer
Cancer gene dependency maps help reveal proteins' relationships
By merging cancer functional genetic data with information on protein interactions, scientists can explore protein complexes at massive scale.
May 17, 2018
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Page 9 - News tagged with protein complex
Diseases, Conditions, Syndromes
Researchers identify key areas of measles virus polymerase to target for antiviral drug development
Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be used as an approach to developing new antiviral drugs to treat the serious ...
Aug 23, 2019
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Medical research
Researchers observe protein degradation in intact brain cells
Neurodegenerative diseases like Alzheimer's, Huntington's or Parkinson's are caused by defect and aggregated proteins accumulating in brain nerve cells that are thereby paralyzed or even killed. In healthy cells this process ...
Jan 23, 2015
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Oncology & Cancer
Breakthrough in knowledge of how some sarcomas arise
The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. Findings now being presented create the opportunity to test new treatments of these forms of sarcoma.
Apr 9, 2019
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Neuroscience
Chemical compound shows promise as alternative to opioid pain relievers
A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according ...
Jul 15, 2013
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Oncology & Cancer
Decreased blood vessel leakage can improve cancer therapy and reduce tumor spread
Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels ...
Mar 23, 2016
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Medical research
New understanding of key enzymes could help to develop new drugs to treat diseases such as cancer and Alzheimer's
New knowledge about the mechanism of specific protein complexes in the body could help in the development of better drugs for the treatment of diseases such as cancer and Alzheimer's, according to research led by the University ...
Apr 25, 2016
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Neuroscience
Fatal cellular malfunction identified in Huntington's disease
Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene ...
Jun 23, 2014
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Genetics
Meet CLAMP: A newly found protein that regulates genes
(Medical Xpress)—A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit flies, bringing them to ...
Jul 16, 2013
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Medical research
Structures of Parkinson's disease-linked proteins offer a framework for understanding how they work together
Scientists at St. Jude Children's Research Hospital have revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases. Leucine-rich repeat kinase 2 (LRRK2) is ...
Dec 21, 2023
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