In hopes of developing a possible treatment for COVID-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses' ability to enter human cells. The potential drug is a short protein ...
Mar 30, 2020
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(Medical Xpress)—In the ongoing quest to design new beneficial molecules or identify potential drugs catalogued in pharmaceutically databases, a critical requirement is determining how a ligand (typically a modulator, or ...
With the end of the pandemic seemingly nowhere in sight, scientists are still very focused on finding new or alternative drugs to treat and stop the spread of COVID-19. In a first-of-its-kind study, researchers at the University ...
Jun 22, 2022
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Over the past two years, scientists have studied the SARS-CoV-2 virus in great detail, laying the foundation for developing COVID-19 vaccines and antiviral treatments. Now, for the first time, scientists at the Department ...
Sep 8, 2022
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A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process.
Nov 3, 2016
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Alzheimer's disease (AD), a severe form of dementia among aged individuals, is caused by accumulation of amyloid-beta (Aβ) peptides in the brain. Numerous types of agents have been developed to suppress the production of ...
Jun 11, 2015
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RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue ...
Jun 24, 2022
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The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C. While cancer researchers ...
Aug 30, 2012
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The human brain contains approximately 86 billion neurons and 600 trillion synapses that exchange signals between the neurons to help us control the various functions of the brain, including cognition, emotion, and memory. ...
Jan 18, 2024
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Amyloid deposition is a hallmark of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). The deposition process is described as a sigmoidal curve in which the misfolded proteins assemble ...
Aug 2, 2023
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