Autism spectrum disorders

Agent reduces autism-like behaviors in mice

National Institutes of Health researchers have reversed behaviors in mice resembling two of the three core symptoms of autism spectrum disorders (ASD). An experimental compound, called GRN-529, increased social interactions ...

Neuroscience

Why some people are more prone to anxiety

Anxiety-prone people can blame serotonin cleanup proteins gone awry in their amygdala, according to research in marmosets recently published in JNeurosci. Targeting the amygdala with anti-anxiety medication could provide ...

Immunology

Scientists develop new mouse model of Hirschsprung's disease

About one in every 5,000 babies is born without enteric neurons in the distal colon resulting in Hirschsprung's disease. Because of the missing neurons, contents of the gut cannot pass normally, resulting in constipation ...

Alzheimer's disease & dementia

Immune cell defect stimulates Alzheimer's

Defects in the gene TREM2 are linked to increased risk of Alzheimer's disease. The gene is required to activate immune cells called microglia in the brain, which help to eliminate the neurotoxic deposits that are typical ...

Genetics

Gene that causes atrial fibrillation discovered

Genetic studies spanning three generations of a Persian Jewish family by researchers at Ben-Gurion University of the Negev (BGU) have identified a gene that causes nighttime atrial fibrillation (AFib).

Medical research

Fail-safe system may lead to cures for inherited disorders

Scientists at the University of California, San Diego School of Medicine have uncovered a previously unknown fail-safe (compensatory) pathway that potentially protects the brain and other organs from genetic and environmental ...

Parkinson's & Movement disorders

Genetic mutation linked to Parkinson's disease

Researchers have discovered a new gene mutation they say causes Parkinson's disease. The mutation was identified in a large Swiss family with Parkinson's disease, using advanced DNA sequencing technology.

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