Psychoactive drugs include all manner of hallucinogens, deliriants, hypnotics and psychedelics. But what is a psychedelic, really? Insofar as many in the field are now moving toward bringing new molecules with presumably ...
Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Oct 10, 2012
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There is nothing magic about the recent increase in interest around the study of psychedelic drugs as potential treatments for patients suffering from a myriad of mental health conditions.
Dec 15, 2023
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Mechanoreceptors in human skin can sense the delicate weight of a butterfly, feel the heat of a nearby flame or a cool drink, understand whether a hand is raised in a fist or a peace sign, and count the pulse of a loved one ...
May 18, 2023
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Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.
Mar 4, 2022
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Researchers at The University of Queensland, working to gain a better understanding of how brain cells work, have discovered the underlying mechanism of a rare genetic mutation that can cause epilepsy.
Jul 8, 2021
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Chemokine receptors, located at the surface of many immune cells, play an important role in cell function. Chemokines are small proteins that bind to these receptors and control the movement and behavior of white blood cells.
Jun 16, 2021
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G protein-coupled receptors (GPCRs) are the largest family of membrane protein receptors. The proteins control how tissues and organs function. More than one-third of current drugs target these receptors.
Nov 5, 2020
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Why is it that some chronic inflammatory bowel diseases, such as Crohn's, affect both the small intestine and the colon, while others, like ulcerative colitis, are restricted to the colon? In order to solve clinical puzzles ...
Jul 3, 2020
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Learned connections between stimuli and reward—like the positive emotions associated with popular brands—have a powerful influence over our future decisions. Scientists have started to discover why.
Apr 2, 2020
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