One powerful DNA-binding protein, the transcription factor PU.1, steals away other transcription factors and recruits them for its own purposes, effectively dominating gene regulation in developing immune cells, according ...
Jun 20, 2018
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Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a cell determine what that cell can do. Among the multiple elements that are involved in the precise regulation of gene ...
Mar 20, 2018
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Approximately once a month, our skin completely renews itself. If this highly coordinated process goes awry, it can lead to a variety of skin diseases, ranging from skin cancer to psoriasis. Cells lining such organs as skin ...
Feb 20, 2018
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Researchers from the University of Eastern Finland have published a textbook on human epigenomics, the study of epigenetic modifications across the entire genome. The book is the first of its kind to focus on epigenomics ...
Feb 19, 2018
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Twenty-five years ago, an unusual inherited form of high blood pressure was first described in an Australian family. Its genetic cause, however, had remained elusive. Using modern sequencing methods, an international research ...
Feb 6, 2018
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Any parent with identical twins knows their two children are actually remarkably different. Identical twins are genetically identical, but they are not identical in gene expressions, a difference attributable to epigenetics. ...
Dec 13, 2017
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Our genomes help to determine who we are - the countless variations between individuals that encode the complexity of tissues and functions throughout the body. Since scientists first decoded a draft of the human genome more ...
Oct 13, 2017
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Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a study reported in a recent issue of the journal mBio. The study demonstrated that histone methyltransferases EZH2/1 ...
Aug 15, 2017
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A treatment for a common childhood blood cancer could become the first gene therapy available in the U.S.
Jul 12, 2017
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Molecular insight into our own DNA is now possible, a field called personal genomics. Such approaches can let us know when we might have cancer-causing alterations in our genes. Well-known examples are the melanoma oncogene ...
Apr 4, 2017
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