Genetics

Handful of genetic changes led to huge changes to human brain

Changes to just three genetic letters among billions led to evolution and development of the mammalian motor sensory network, and laid the groundwork for the defining characteristics of the human brain, Yale University researchers ...

Genetics

The influence of the mother: Maternal epigenetic inheritance

(Medical Xpress) -- A study published in Genes and Development from scientists at the Friedrich Miescher Institute for Biomedical Research pinpoints the importance of maternal epigenetic influences during early embryogenesis ...

Genetics

Early lead exposure affects gene expression throughout life

A team of researchers led by North Carolina State University biologists Cathrine Hoyo and Randy Jirtle have found links between lead exposure in children and epigenetic alterations in regulatory regions of genes that are ...

Autism spectrum disorders

Gene regulator in brain's executive hub tracked across lifespan

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings of the study ...

Genetics

New method created for identifying genes behind brain tumors

Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...

Medical research

Search for epigenetic decoder leads scientists to Rett Syndrome

(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...

Oncology & Cancer

Mysterious gene transcripts after cancer therapy

Tumor suppressor genes protect cells from malignant transformation. If they are turned off as a result of chemical modifications in DNA, called epigenetic labels, this contributes to the development of cancer. As opposed ...

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