HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals ...
May 4, 2015
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Understanding the immune response triggered by the mosquito-borne Chikungunya virus (CHIKV) is key to developing effective treatments. Now, an international team led by A*STAR researchers has shown that a cell surface protein—the ...
Apr 15, 2015
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More than 60 percent of the world's population is infected with a type of herpes virus called human cytomegalovirus. The virus replicates by commandeering the host cell's metabolism but the details of this maneuver are unclear.
Mar 23, 2015
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The Human Immunodeficiency Virus (HIV) mutates very rapidly and circulates in many different strains. The strain of HIV someone is first infected with, and its capacity to replicate in the body, can have a lasting influence ...
Feb 18, 2015
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In this week's issue of Science, researchers at Gilead Sciences, Inc. and Beryllium reveal new details about how the hepatitis C virus (HCV) replicates its genome. HCV is estimated to affect 150-200 million people worldwide ...
Feb 12, 2015
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Saint Louis University research findings published in the December issue of Antimicrobial Agents and Chemotherapy report a family of molecules known as nucleotidyltransferase superfamily (NTS) enzyme inhibitors are promising ...
Dec 18, 2014
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A team of scientists, led by researchers at The Wistar Institute, has found that an infection with herpes simplex virus 1 (HSV-1) causes rearrangements in telomeres, small stretches of DNA that serve as protective ends to ...
Dec 11, 2014
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Enzymes inside cells that normally repair damaged DNA sometimes wreck it instead, researchers at the Stanford University School of Medicine have found. The insight could lead to a better understanding of the causes of some ...
Nov 26, 2014
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Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's disease.
Nov 25, 2014
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Doctors have long been mystified as to why HIV-1 rapidly sickens some individuals, while in others the virus has difficulties gaining a foothold. Now, a study of genetic variation in HIV-1 and in the cells it infects reported ...
Nov 20, 2014
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