Oncology & Cancer

Sure, cancer mutates, but it has other ways to resist treatment

Because of advances in drug design and precision medicine, researchers have been able to target certain molecules within a cell at the root of a particular disease and to develop specific therapies to undo their damages. ...

Oncology & Cancer

Synthetic macromolecules kill multidrug-resistant cancer cells

Cancer continues to be a deadly threat to more than 14 million people who are diagnosed each year around the world. At the same time, five-year survival rates have been steadily improving over the last three decades to nearly ...

Oncology & Cancer

How mathematics is helping to fight cancer

Nearly half of Canadians will develop cancer in their lifetime, according to the Canadian Cancer Society. Globally, cancer is the second leading cause of death.

Oncology & Cancer

Switching on survival signalling to drive drug resistance

Researchers at Queen Mary University of London have discovered that the loss of a single protein- PHLDA1- is sufficient for the development of drug resistance to a type of targeted therapy in endometrial and HER2-positive ...

Oncology & Cancer

Why do perfectly good cancer treatments suddenly stop working?

Kris Wood, PhD, had been going full tilt for more than six months, ever since he'd been hired to the faculty in the Department of Pharmacology and Cancer Biology at Duke. He was working 12 stressful hours a day, adjusting ...

Oncology & Cancer

Genetic targets to chemo-resistant breast cancer identified

Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.

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