Ewing sarcoma is a cancer of bone or its surrounding soft tissue that primarily affects children and young adults. A hallmark of Ewing sarcoma is a translocation event that results in the fusion of an RNA binding protein, ...
Nov 17, 2014
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Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting ...
Jun 9, 2013
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Amyotrophic lateral sclerosis (ALS) is an incurable disease of the central nervous system. In most cases, ALS is fatal within a short period following diagnosis. However, people sometimes live with the disease for decades, ...
Apr 16, 2019
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Once HIV-1 has hijacked a host cell to make copies of its own RNA genome and viral proteins, it must assemble these components into new virus particles. The orchestration of this intricate assembly process falls to a viral ...
Feb 27, 2015
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Pancreatic cancer presents a challenging prognosis, marked by a five-year overall survival rate of merely 12.5%. Diagnosis frequently occurs at an advanced stage, characterized by metastasis to distant sites. The intricate ...
Jan 11, 2024
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A common thread ties seemingly unlinked disorders like Alzheimer's disease and type II diabetes together. This thread is known as protein aggregation and happens when proteins clump together. These complexes are a hallmark ...
Oct 22, 2017
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ALS—amyotrophic lateral sclerosis—is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow. In a cruel twist, ...
Aug 20, 2018
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A new paper describes the role of two RNA-binding proteins in the development of sarcoma and carcinoma cancers, highlighting the important and emerging role of RNA-binding proteins in cancer research and offering a new avenue ...
Apr 24, 2024
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Nagoya University-led research identifies role for neuronal protein interaction in preventing frontotemporal lobar degeneration, a dementia that starts in middle age.
Feb 13, 2017
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Learning requires constant reconfiguration of the connections between nerve cells. Two new studies now yield new insights into the molecular mechanisms that underlie the learning process.
Dec 20, 2013
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