Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically increases the ...
Dec 21, 2012
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Cancer biologists have known for decades that even the most potent cancer-causing genes do not act alone. Yet, identifying which combinations of genetic changes can cause a tumor to form and disease to progress remains a ...
Dec 5, 2012
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Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals.
Nov 15, 2012
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While studying Parkinson's disease, an international research group made a discovery which can improve industrial protein synthesis for therapeutic use. They managed to understand a novel function of non-protein coding RNA: ...
Oct 16, 2012
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Rapamycin, a drug used to prevent rejection in transplants, could delay the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's. This is the main conclusion of a study published in the Nature in which ...
Oct 15, 2012
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(Medical Xpress)—Until recently, medical researchers had little hope of experimentally manipulating naïve T cells to study their crucial roles in immune function, because they were largely impenetrable, says polymer scientist ...
Oct 11, 2012
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There are approximately 400,000 people in the United States with multiple sclerosis. Worldwide, the number jumps to more than 2.1 million people. Rather than a one-size-fits-all approach to treating the millions with multiple ...
Sep 26, 2012
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(Medical Xpress)—Cardiac stress, for example a heart attack or high blood pressure, frequently leads to pathological heart growth and subsequently to heart failure. Two tiny RNA molecules play a key role in this detrimental ...
Sep 25, 2012
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(Medical Xpress)—Long stretches of DNA once considered inert dark matter appear to be uniquely active in a part of the brain known to control the body's 24-hour cycle, according to researchers at the National Institutes ...
Sep 24, 2012
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(Medical Xpress)—Work by Michigan Technological University biologist Xiaoqing Tang is yielding new insights into how a tiny snippet of genetic material can promote healthy insulin production in mice.
Sep 20, 2012
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