Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (HR), a key mechanism for ...
Dec 3, 2018
0
44
Scientists at the Francis Crick Institute and UCL have studied how proteins accumulate in the wrong parts of brain cells in motor neuron disease, and have demonstrated how it might be possible, in some cases, to reverse this.
Aug 6, 2021
0
848
The Molecular Neuroscience Unit at the Okinawa Institute of Science and Technology (OIST) has made an important breakthrough by connecting sensory neurons' survival and pathology with the way messenger RNAs (mRNAs) are transported ...
Oct 31, 2023
0
0
In the first study of its kind, researchers from Sanford Burnham Prebys have uncovered molecular changes within the aging brains of individuals with Down syndrome that could help explain their cognitive challenges, including ...
Nov 15, 2021
0
112
Ten days after receiving a second dose of a messenger RNA, or mRNA, vaccine for COVID-19, patients without COVID-19 symptoms are far less likely to test positive and unknowingly spread COVID-19, compared to patients who have ...
Mar 11, 2021
0
19
A team of researchers at the Icahn School of Medicine at Mount Sinai, working with colleagues from several other U.S. institutions, has found a possible RNA-related clue that might explain why approximately twice as many ...
Addressing problems with diagnosing and treating breast cancer, scientists at EPFL have developed EMBER, a tool that integrates breast cancer transcriptomic data from multiple databases. EMBER can improve precision oncology ...
Jul 19, 2024
0
11
Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma. A research team from University Hospital Zurich and the University of Oxford ...
Jul 5, 2019
0
1
Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes. In a new study, researchers evaluated the effects of over 300 pairwise ...
Feb 14, 2020
0
214
Researchers have identified specific portions of the genetic codes of the COVID-19 and SARS viruses that may promote the viruses' lifecycles. The new technique is researchers' first tool for determining what genetic sequences ...
Jun 2, 2020
0
2
