Parkinson's & Movement disorders

Gene-silencing study finds new targets for Parkinson's disease

Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson's disease. The findings also may be ...

Medications

Promising results for new acute porphyria treatment

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment ...

Medical research

Heading for regeneration

The rabbit can't do it, neither can a frog, but zebrafish and axolotls can and flatworms are true masters of the craft: Regeneration. Why some animals can re-grow lost body parts or organs while others cannot remains a big ...

Diseases, Conditions, Syndromes

New mechanism to control human viral infections discovered

A team of researchers, co-led by a University of California, Riverside professor, has found a long-sought-after mechanism in human cells that creates immunity to influenza A virus, which causes annual seasonal epidemics and ...

Oncology & Cancer

Double whammy: RNAi enhances lung cancer therapy

Non-small cell lung cancer (NSCLC), the most common form of lung cancer, is usually treated with surgery and chemotherapy. However, a small group of patients can also be helped by treatment with tyrosine kinase inhibitors ...

Medical research

RNAi therapy mitigates preeclampsia symptoms

A collaboration of scientists from the University of Massachusetts Medical School, Beth Israel Deaconess Medical Center and Western Sydney University, have shown that an innovative new type of therapy using small interfering ...

Oncology & Cancer

Hedgehog pathway key in tamoxifen-resistant breast CA

(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh signaling molecules, ...

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