Medical research

New clues to the structural dynamics of BK channels

BK channels (large-conductance, Ca2+-dependent K+ channels) are essential for the regulation of important biological processes such as smooth muscle tone and neuronal excitability. New research shows that BK channel activation ...

Cardiology

Atherosclerosis: Induced cell death destabilizes plaques

Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet (LMU) team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death ...

Cardiology

Genetic mutation linked to aortic dissection in the chest

Researchers at Umeå University in Sweden have discovered a genetic mutation that can cause dissection of the thoracic aorta, which is the body's main artery. The mutation leads to an impaired function of the smooth muscle ...

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