Oncology & Cancer

Researchers find key to help treat different cancers

Yale Cancer Center (YCC) scientists have uncovered the workings of a metabolic pathway or "gauge" that lets cancer cells detect when they have enough nutrients around them to grow. The researchers hope that drugs designed ...

Medical research

'Natural killers' may help treat advanced solid cancerous tumors

An internal battle over oxygen can lead to major setbacks for people battling solid malignant tumors such as lung and brain cancers. Many solid tumors develop a severe lack of oxygen because they grow into large masses where ...

Oncology & Cancer

New vaccine strategy boosts T-cell therapy

A promising new way to treat some types of cancer is to program the patient's own T cells to destroy the cancerous cells. This approach, termed CAR-T cell therapy, is now used to combat some types of leukemia, but so far ...

Oncology & Cancer

Bacteria engineered as Trojan horse for cancer immunotherapy

The emerging field of synthetic biology—designing new biological components and systems—is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently ...

Oncology & Cancer

Childhood leukemia cannot hide from the immune system

St. Jude Children's Research Hospital scientists have evidence that children with acute lymphoblastic leukemia mount a robust immune response to their cancer. The findings, which appear today in the journal Science Translational ...

Oncology & Cancer

Molecular chatter makes for a 'hot tumor'

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

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