Immunology

Liver tropism is key for B cell deletion immunotherapy

Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding receptors, called Fc receptors, on other immune cells bind anti-CD20 ...

Medical research

Towards a better understanding of inherited hearing loss

A team of researchers led by Dr. Michel Cayouette at the IRCM made an important discovery, published online yesterday by the scientific journal Developmental Cell, that could better explain some inherited forms of hearing ...

Oncology & Cancer

New knowledge on molecular mechanisms behind breast cancer

Researchers at University of Copenhagen have gained more insight into the molecular mechanisms of importance for, for example, cancer cell growth and metastasis. The research objective is improved and more targeted drugs. ...

Diseases, Conditions, Syndromes

Sugar coating reveals black death

Even today, the lives of humans and animals are claimed by plague. A new antibody-based detection method can be used to reliably and sensitively identify plague in patient serum and other biological samples. The antibody ...

Diseases, Conditions, Syndromes

Effective vaccination against borreliosis possible

"Borreliosis" or "Lyme disease" is caused by the bacterium "Borrelia burgdorferi". In Austria approximately 16,000 people fall ill with borreliosis annually following a tick bite. Roughly every fifth tick in Austria carries ...

Neuroscience

How the brain folds to fit

During fetal development of the mammalian brain, the cerebral cortex undergoes a marked expansion in surface area in some species, which is accommodated by folding of the tissue in species with most expanded neuron numbers ...

Medications

Pain reliever naproxen shows anti-viral activity against flu

The over-the-counter anti-inflammatory drug naproxen may also exhibit antiviral activity against influenza A virus, according to a team of French scientists. The finding, the result of a structure-based investigation, is ...

Diseases, Conditions, Syndromes

Combating the deathly Coronavirus

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate ...

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