Genetics

More than 3,000 epigenetic switches control daily liver cycles

(Medical Xpress)—When it's dark, and we start to fall asleep, most of us think we're tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level of individual ...

Medical research

Molecular switch identified that controls key cellular process

The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.

Oncology & Cancer

Gene inactivation drives spread of melanoma: study

Why do some cancers spread rapidly to other organs and others don't metastasize? A team of UNC researchers led by Norman Sharpless, MD, have identified a key genetic switch that determines whether melanoma, a lethal skin ...

Parkinson's & Movement disorders

Molecular 'on-off' switch for Parkinson's disease discovered

(Medical Xpress) -- Scientists at the Medical Research Council (MRC) Protein Phosphorylation Unit at the University of Dundee have discovered a new molecular switch that acts to protect the brain from developing Parkinson's ...

Medical research

Liver fat gets a wake-up call that maintains blood sugar levels

A Penn research team, led by Mitchell Lazar, MD, PhD, director of the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine, University of Pennsylvania, reports in Nature Medicine that mice in ...

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