CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway. However, ...
Jun 12, 2024
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When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets ...
May 21, 2024
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Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors. One reason for the ...
May 30, 2024
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Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.
Jun 12, 2024
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The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor. Over time, the tumor shapes this ...
Jun 13, 2024
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Ciliopathies are multisystem disorders characterized by the dysfunction of motile and/or non-motile cilia, which show common clinical manifestations of ciliopathies include retinal degeneration, mental retardation, renal ...
Jun 7, 2024
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Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms. The tumor microenvironment plays a pivotal role in fostering ...
May 22, 2024
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Scientists should focus on the interactions between T and B cells to find better treatments for autoimmune disorders, such as rheumatoid arthritis, according to a new study from the University of Surrey. The study has been ...
Jun 4, 2024
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Madeleine Lehander from the Hematology Unit/HERM, at the Department of Medicine, Huddinge (MedH), is defending her thesis "Exploring T Cell Mediated Immunotherapy against Therapy Resistant Leukemic Stem Cells," on 24 May ...
May 20, 2024
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Penn Medicine's patients of color are far less likely than white patients to receive a novel gene therapy pioneered there and hailed as a cure for some blood cancers, new research shows.
Jun 11, 2024
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