Medical research

Mathematical modelling to tackle metabolic diseases

Predictive mathematical models of signalling pathways are powerful biological tools that could be used for drug development. Using a similar approach, European scientists developed a computational model for answering research ...

Oncology & Cancer

Fighting cancer with the immune system

The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic ...

Neuroscience

Reach2HD, a Phase II study in Huntington's disease, launched

The Huntington Study Group (HSG), under the leadership of Ray Dorsey, M.D. with Johns Hopkins Medical and Diana Rosas, M.D. with Massachusetts General Hospital, is conducting a clinical trial in Huntington's disease (HD) ...

Oncology & Cancer

A possible target for broad-range HPV therapeutics emerges

(Medical Xpress) -- Among viruses, human papilloma virus (HPV) stands out: with more than 180 distinct isotypes or variations catalogued to date, it presents an extremely difficult target for broad-range treatments. And while ...

Oncology & Cancer

A thought-provoking new therapeutic target for brain cancer?

Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...

Oncology & Cancer

Glioblastoma multiforme in the Dock

Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. ...

Diseases, Conditions, Syndromes

Potential new drug target in Lou Gehrig's disease

Two proteins conspire to promote a lethal neurological disease, according to a study published online this week in the Journal of Experimental Medicine.

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