Alzheimer's disease & dementia

Drug compound halts Alzheimer's-related damage in mice

Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells. Such tangles are a hallmark of ...

Alzheimer's disease & dementia

Using tau imaging as diagnostic marker for Alzheimer disease

The accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tracers, including [18F]-AV-1451, bind to tau in neurofibrillary ...

Alzheimer's disease & dementia

Old drug offers new hope to treat Alzheimer's disease

Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia (FTD). Salsalate ...

page 6 from 9