Alzheimer's disease & dementia

Redefined Alzheimer's biology has implications for drug design

Despite the 25-year focus on the build-up in brain tissues of one protein, amyloid beta, as the purported origin of Alzheimer's disease (AD), a new study argues that it is likely triggered instead by the failure of a system ...

Neuroscience

Revealing roles of dementia proteins in normal memory

New research has revealed how the tau protein, a critical element in the formation of Alzheimer's disease, is also involved in normal learning processes in the healthy brain—potentially providing a focal point for future ...

Alzheimer's disease & dementia

Scientists block action of hallmark dementia protein in mice

A research team at King's College London has used a new approach to study a hallmark dementia protein called tau in mice, revealing that a drug called phenylbutyrate can protect against damage caused by the protein.

Alzheimer's disease & dementia

Designer compound may untangle damage leading to some dementias

In a study of mice and monkeys, National Institutes of Health funded researchers showed that they could prevent and reverse some of the brain injury caused by the toxic form of a protein called tau. The results, published ...

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