Mutations to the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer, according to results published in Cancer Research, a journal of the American Association for ...
May 24, 2018
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The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism. Genetic diseases or an imbalanced diet, with too much red meat or deficiencies in B vitamins and folic acid, ...
May 16, 2018
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(HealthDay)—The correlation between the apolipoprotein E (APOE) gene allele APOE-ε4 and cerebrospinal fluid (CSF) tau levels is stronger among women than men, according to a study published online May 7 in JAMA Neurology.
May 9, 2018
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Improving the trafficking of cellular proteins in brain cells holds possibilities for new treatments and even prevention for Alzheimer's disease, results of a new study suggest.
Mar 1, 2018
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InSysBio continues to investigate the mechanisms underlying Alzheimer's disease (AD) using the quantitative systems pharmacology (QSP) modeling approach. The QSP model describing the tau protein was published in PLOS ONE.
Feb 28, 2018
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Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset dementia, and can lead to personality changes, impaired speaking and motor dysfunction. While most cases occur sporadically, several ...
Feb 26, 2018
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Despite the 25-year focus on the build-up in brain tissues of one protein, amyloid beta, as the purported origin of Alzheimer's disease (AD), a new study argues that it is likely triggered instead by the failure of a system ...
Feb 7, 2018
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Alzheimer's disease is a devastating brain illness that affects an estimated 47m people worldwide. It is the most common cause of dementia in the Western world. Despite this, there are currently no treatments that are effective ...
Jan 5, 2018
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(HealthDay)—Patterns of cortical β-amyloid (Aβ) and tau are not different for patients with Parkinson's disease (PD) who are cognitively normal (PD-CN) or with mild cognitive impairment (MCI) and for healthy adults, according ...
Dec 12, 2017
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Deep within our brains is a dense forest of 100 billion nerve cells. Each of those cells has about 15,000 dendrites that branch out to connect with dendrites from other nerve cells, generating more than 100 trillion points ...
Nov 16, 2017
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