Medical research

Blocking two enzymes could make cancer cells mortal

EPFL scientists have identified two enzymes that protect chromosomes from oxidative damage and shortening. Blocking them might be a new anticancer strategy for stopping telomerase, the enzyme that immortalizes tumors.

Oncology & Cancer

Targeting telomerase as therapeutic strategy for melanoma

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar ...

Diseases, Conditions, Syndromes

Telomerase-expressing liver cells regenerate the organ, researchers find

Liver stem cells that express high levels of telomerase, a protein often associated with resistance to aging, act in mice to regenerate the organ during normal cellular turnover or tissue damage, according to a study by researchers ...

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