Oncology & Cancer

Thwarting protein production slows cancer cells' malignant march

Protein production or translation is tightly coupled to a highly conserved stress response that cancer cells rely on for survival and proliferation, according to Whitehead Institute researchers. In mouse models of cancer, ...

Medical research

Scientists find 3D structure of key drug target for diabetes

An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney ...

Oncology & Cancer

Self-perpetuating signals may drive tumor cells to spread

A team of international researchers from Duke-NUS Graduate Medical School Singapore and the Johns Hopkins University School of Medicine (USA) has identified a self-perpetuating signaling circuit inside connective tissue cells ...

Oncology & Cancer

Important advance in the fight against skin cancer

Researchers from the Hospital del Mar Medical Research Institute (IMIM), lead by Lluís Espinosa, have identified a new function of the IB protein that is key in the development of squamous-cell carcinoma, a type of skin ...

Cardiology

Cells make costume changes for cardiac regeneration

(Medical Xpress)—If the heart following a heart attack is not sufficiently supplied with blood, heart tissue dies. In adult humans, the ability to heal itself is hardly developed. Scientists from the Max Planck Institute ...

Oncology & Cancer

Immunohistochemistry effectively detects ALK rearrangement

ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma ...

page 38 from 40