In 2012, a team of scientists headed by Professor Benedikt Berninger first succeeded in reprogramming connective tissue cells present in the brain into neurons. Until now, however, it was completely unknown which intermediate ...
Jul 2, 2018
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The tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, according to new research conducted at The Wistar Institute, which provided mechanistic insight into tumorigenesis mediated by ...
Jun 26, 2018
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Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease.
Jun 25, 2018
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One powerful DNA-binding protein, the transcription factor PU.1, steals away other transcription factors and recruits them for its own purposes, effectively dominating gene regulation in developing immune cells, according ...
Jun 20, 2018
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The first genetic marker for the bone tumour, osteoblastoma, has been discovered by scientists at the Wellcome Sanger Institute and their collaborators. Whole-genome and transcriptome sequencing of human bone tumours revealed ...
Jun 12, 2018
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Plasma B cells, which move through the body releasing antibodies, are an important component of the body's fight against viral infections and other invaders. They are relatively rare, however, and increasing their ranks is ...
Apr 18, 2018
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As Associate Research Director, Professor Anne O'Garra helps to promote the Crick's collaborative vision, encouraging scientists from different disciplines to work together. But when it comes to her own research, does she ...
Apr 17, 2018
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A far-reaching study conducted by scientists at Cincinnati Children's reports that the Epstein-Barr virus (EBV)—best known for causing mononucleosis—also increases the risks for some people of developing seven other major ...
Apr 16, 2018
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St. Jude Children's Research Hospital scientists have identified a key molecule that serves as a "security chief" to help the immune system quickly recognize and fight infections with dangerous gram-negative bacteria like ...
Mar 23, 2018
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A switch has been discovered that instructs blood vessel cells to become blood stem cells during embryonic development in mice. Using single-cell technology, researchers from the Wellcome Sanger Institute in Cambridge and ...
Mar 20, 2018
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