The split personality of a nerve cell illustrates a puzzle. Nerve cells are divided in two domains – the axon sends signals and the dendrites receive them. Axonal and dendritic proteins embedded in the membrane at either ...
Feb 22, 2018
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Known as much for its complexity as its vital role in regulating cellular and organismal growth, the mechanistic target of rapamycin complex 1 (mTORC1) pathway has seemingly been acting in mysterious ways.
Jan 7, 2015
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(Medical Xpress)—Scientists have described a new family of proteins that appear to play a key role in cancer and might be targets for future cancer drugs. A major new study in the journal Nature sets out the structure of ...
Dec 1, 2013
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When the central nervous system is injured, oligodendrocyte precursor cells (OPC) migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes ...
Jul 31, 2013
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(Medical Xpress)—Cystic fibrosis is caused by a mutation in the gene that encodes a particular protein, known as the cystic fibrosis transmembrane conductance regulator (or CFTR). Although this discovery was made 25 years ...
Jul 9, 2013
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When DNA that turns up in the wrong place in mammalian cells, the innate immune system reacts by secreting interferons. The structure and mode of action of the enzyme that mediates this response have now been elucidated.
Jun 4, 2013
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(Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important regulator for synapse growth, ...
Apr 25, 2013
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(Medical Xpress)—Researchers from the University of Tokyo have uncovered the physical layout of a transmembrane protein that the tiny organism Archaea relies on to keep toxins out of its cells. The protein, the team explains ...
A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene ...
Mar 12, 2012
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The Lung Institute of WA (LIWA) has recently made a breakthrough in the search for a drug to improve the quality of life of patients with Cystic Fibrosis (CF).
Nov 28, 2011
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