The resistance to cancer treatment is often credited to the heterogenous cellular nature within a tumor. The tumor cell-cell interaction and cell-microenvironment have a key role in the invasion and progression of tumors ...
In one of the largest studies of its kind, researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival. The team, ...
Apr 10, 2019
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Using artificial intelligence, Garvan Institute researchers have found potential cancer drivers hidden in so-called 'junk' regions of DNA, opening up possibilities for a new approach to diagnosis and treatment.
Jul 3, 2024
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A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.
May 23, 2024
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Immunotherapy is already improving treatment options for many cancer types, but research groups keep exploring ways to boost the body's immune response against the tumor.
Feb 14, 2024
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Even for killer T cells—specialized immune cells—seeking and destroying cancer cells around the clock can be exhausting. If scientists can understand why killer T cells become exhausted, then they can create more resilient ...
Sep 20, 2023
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Almost one in five Danes experiences depression during their lives. A new study from Aarhus University now shows that the genetic risk of depression can be linked to an increased genetic risk of other psychiatric diagnoses. ...
Aug 29, 2023
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Researchers with the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborators have shown that immature natural killer (NK) cells are present in patients with triple-negative ...
Mar 28, 2023
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In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells. ...
Nov 28, 2022
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Scientists from Roswell Park Comprehensive Cancer Center have shed light on a different way of overcoming mechanisms of resistance to specific therapeutic agents used to treat cancer. In a new article published March 1 in ...
Mar 3, 2022
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