Medical research

Mapping metabolism with a novel imaging technique

Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could ...

Oncology & Cancer

Metabolic reprogramming of tumor-associated macrophages

Cancer is a complex disease and although billions of dollars have been spent on finding safe and effective therapeutics for it, there is still scope for significant development. Researchers have targeted a variety of biological ...

Medical research

Lung tumors hijack metabolic processes in the liver, study finds

University of California, Irvine scientists who study how circadian rhythms—our own body clocks—control liver function have discovered that cancerous lung tumors can hijack this process and profoundly alter metabolism.

Medical research

Key enzyme plays roles as both friend and foe to cancer

A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of Illinois at Chicago ...

Oncology & Cancer

Metabolic profiles essential for personalizing cancer therapy

One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism shows that one metabolism-targeted cancer therapy will not fit all. That means that ...

Genetics

Researchers relate DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off", and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

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