Oncology & Cancer
High-fat diet linked to nitric oxide levels, cancer development
It has long been hypothesized that dietary habits can precede and even exacerbate the development of cancer.
May 17, 2022
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419
News tagged with tumor microenvironment
Medical research
Study finds nanomedicine targeting lymph nodes key to triple negative breast cancer treatment
Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer.
May 12, 2022
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116
Immunology
Study finds Stat5-/- CD4+ T cells elicit an anti-melanoma effect by CD4+ T cell remolding and Notch1 activation
Tumor-infiltrating lymphocytes (TILs) play a key role in the antitumor immune response and various types of immunotherapies. Recently, studies have shown that CD4+ T cells and CD8+ T cells are equally important for an efficient ...
May 12, 2022
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Oncology & Cancer
Patient-derived micro-organospheres enable cutting-edge precision oncology
A patient's tumor cell response to therapy is affected by many factors, including genetic alterations, tumor microenvironment, and intratumoral heterogeneity. This can make it extremely difficult to determine optimum treatment ...
May 05, 2022
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10
Medical research
A promising combination therapy for triple-negative breast cancer
Researchers at Baylor College of Medicine and collaborating institutions have identified a combination therapy for treating triple-negative breast cancer (TNBC) that results in durable tumor regression in an animal model ...
Apr 27, 2022
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Oncology & Cancer
T-cell interactions vary between tumor microenvironments
A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according ...
Apr 15, 2022
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59
Oncology & Cancer
Exploring cancer maps
Melanoma is a somewhat unusual cancer—one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.
Apr 14, 2022
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52
Oncology & Cancer
Recurrent non-invasive breast tumors may not always be related to the primary lesion
More than 10 percent of cases of recurrent ductal carcinoma in situ (DCIS) of the breast were "de novo" tumors that occurred independently of the primary lesion and had distinct genetic alterations, according to data presented ...
Apr 10, 2022
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Oncology & Cancer
Cardamonin shows promise for treating aggressive breast cancer
Cardamonin—a natural compound found in the spice cardamom and other plants—could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells. The findings also show ...
Apr 03, 2022
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Oncology & Cancer
Biologists discover signaling pathways potentially associated with pancreatic cancer
Kathleen DelGiorno, assistant professor of cell and developmental biology, her lab and collaborators at the Salk Institute have discovered some of the specific signaling molecules involved in tumor progression in pancreatic ...
Apr 01, 2022
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