British researchers have discovered that an epigenetic protein called EZH2 delays the development of acute myeloid leukemia (AML) but then switches sides once the disease is established to help maintain tumor growth. The ...
Mar 19, 2019
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Cells translate their genetic material at rapid rates with exquisite precision to reproduce, repair damage or even combat disease. But the process can deregulate and give rise to disease. Byproducts of errant processes can ...
Aug 17, 2021
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Lack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the tissue, the body has innate mechanisms that "kick in" to make the cells of the hypoxic ...
Sep 19, 2019
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A Mayo Clinic study is shedding light on why some rheumatoid arthritis patients respond poorly when treated with tumor necrosis factor inhibitors, part of a class of drugs called biologics. It comes down to proteins: specifically, ...
Nov 13, 2016
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Targeted cancer cell therapies using man-made proteins dramatically shrink many tumors in the first few months of treatment, but new research from Johns Hopkins scientists finds why the cells all too often become resistant, ...
Jun 13, 2012
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A possible new target for breast cancer therapy comes from the discovery that the Tyk2 protein helps suppress the growth and metastasis of breast tumors, as reported in Journal of Interferon & Cytokine Research, a peer-reviewed ...
Oct 5, 2011
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Researchers at Winship Cancer Institute of Emory University have identified a new function for a gene that normally prevents the development of cancer.
Mar 1, 2012
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The fight against deadly forms of brain cancer, such as glioblastoma, could soon benefit from a major breakthrough, thanks to A*STAR researchers. The team has found a new link between cancer cell growth and its microenvironment.
May 6, 2016
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Scientists have identified thousands of previously ignored genetic mutations that, although rare, likely contribute to cancer growth. The findings, which could help pave the way to new treatments, are published in PLOS Computational ...
Apr 20, 2017
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Researchers have discovered a method for simultaneously visualizing gene number and protein expression in individual cells. The fluorescence microscopy technique could permit a detailed analysis of the relationship between ...
Sep 22, 2011
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