Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, ...
Apr 9, 2018
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Researchers at Okayama University describe in the journal Scientific Reports the role of an extracellular protein, versican, in regulating tumor growth and providing a newly formed network of blood vessels to further nourish ...
Mar 27, 2018
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Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps ...
Mar 26, 2018
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A study by Massachusetts General Hospital (MGH) investigators finds that, in mouse models, cancer cells from metastatic lymph nodes can escape into the circulation by invading nodal blood vessels, leading to the development ...
Mar 22, 2018
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A new UC San Francisco study has shown that a cancer-killing ("oncolytic") virus currently in clinical trials may function as a cancer vaccine—in addition to killing some cancer cells directly, the virus alerts the immune ...
Feb 13, 2018
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Actively growing tumors have a high demand for oxygen and nutrients. Therefore, they stimulate the growth of blood vessels through a process called angiogenesis. If tumor-associated angiogenesis is suppressed, it may limit ...
Jan 24, 2018
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Aggressive cancers like glioblastoma and metastatic breast cancer have in common a siren call that beckons the bone marrow to send along whatever the tumors need to survive and thrive.
Jan 23, 2018
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St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children. Previously, scientists thought the cancer arose from ...
Jan 8, 2018
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Using a mathematical modeling approach, scientists have found that certain parameters of tumor growth in mice can predict the effectiveness of drugs that block formation of tumor-nourishing blood vessels. The findings are ...
Dec 21, 2017
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A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells. Specifically, when tumor cells ...
Nov 21, 2017
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