Oncology & Cancer

Overstuffed cancer cells may have an Achilles' heel

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry ...

Genetics

Weill Institute researchers uncover basic cell pathway

Although all cells in an organism have the same DNA, cells function differently based on the genes they express. While most studies of gene expression focus on activities in the cell's nucleus, a new Cornell study finds that ...

Diseases, Conditions, Syndromes

Combating fungal diseases

(Medical Xpress) -- Scientists at the Friedrich Miescher Institute for Biomedical Research have discovered a potential new approach for inhibiting the growth of pathogenic fungi. Their findings on the mechanism in question ...

Medical research

Complex cellular machine visualized to yield new insights in cancer

Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein ...

Genetics

Effects of genes often influenced by network

When many genes regulate a single trait, they commonly work together in large clusters or 'networks". Taking this into account allows better predictions of how an individual's genetic make-up affects the trait concerned. ...

Genetics

Recycling histones through transcription

Cells reuse a part of the histones which are used to pack DNA, according to a current study by Karolinska Institutet. The study, which is published in the journal Genome Research, was conducted on yeast cells, but it is likely ...

Oncology & Cancer

Spotting DNA repair genes gone awry

Researchers led by Ludwig Cancer Research scientist Richard Kolodner have developed a new technique for sussing out the genes responsible for helping repair DNA damage that, if left unchecked, can lead to certain cancers.

Genetics

Yeast against the machine: Bakers' yeast could improve diagnosis

It's easier than ever to sequence our DNA, but doctors still can't exactly tell from our genomes which diseases might befall us. Professor Fritz Roth is setting out to change this by going to basics—to our billion-year-old ...

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